PEDIATRICS Vol. 81 No. 5 May 1988, pp. 650-656
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Hearing Loss in Infants With Persistent Fetal Circulation

Karen D. Hendricks-Muñoz MD, MPH1 and Joseph P. Walton PhD1

1 From the Division of Neonatology, Department of Pediatrics, and Division of Otolaryngology, Department of Surgery, University of Rochester School of Medicine, Rochester, New York

Infants with the diagnosis of persistent fetal circulation were evaluated for hearing loss. From Jan 1, 1982, to Jan 1, 1984, 28 infants with this diagnosis were retrospectively identified, and 18 were evaluated by formal audiologic testing. Additionally, 22 infants were prospectively followed by serial auditory evaluation from Jan 1, 1984, to Jan 1, 1986. Of the 40 infants evaluated, 21 were identified as having hearing impairment (52.5%), 14 of whom required hearing aids. For 82% of those retrospectively identified hearing-impaired infants who required hearing aids, parental concern was expressed for their lack of hearing acuity. This factor could have aided in the earlier recognition of these infants' impairment. Among those infants followed prospectively, formal audiologic testing, in some cases serially, was needed to diagnose a progressive hearing loss that was expressed at 6 to 8 months after discharge from the neonatal intensive care unit. Perinatal factors associated with the development and management of persistent fetal circulation were identified and compared in infants with comfirmed hearing loss and those with normal hearing. Variables related to those infants with hearing loss were as follows: degree of alkalosis, duration of ventilation, and possibly use of furosemide. We concluded from these results that infants with persistent fetal circulation have an extremely high incidence of sensorineural hearing loss and suggest serial formal audiologic evaluations to aid in detection of hearing-impaired infants.

Key Words: hearing loss • neonate • persistent fetal circulation

Submitted on March 23, 1987
Accepted on July 10, 1987




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