1 From the Department of Dermatology, The Hospital for Sick Children, and the Department of Immunology, Institute of Child Health, London
Five infants with a triad of symptoms comprising generalized erythroderma, failure to thrive, and diarrhea are presented. All of these children demonstrated significant immunologic abnormalities. This is a recognizable clinical syndrome that reflects immunodeficiency; however, the responsible immunodeficiencies do not appear to be the same in every case. Early investigation and appropriate therapy may considerably reduce morbidity, and mortality in children with this syndrome.
Key Words: erythroderma diarrhea failure to thrive immunodeficiency infancy
Revised on October 20, 1986
Accepted on December 19, 1986
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