PEDIATRICS Vol. 81 No. 1 January 1988, pp. 173-174
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Vitamin Dosages for Premature Infants

HARRY L. GREENE MD1 and BARRY L. PHILLIPS MD2

1 Division of Gastroenterology and Nutrition, Vanderbilt University Medical Center, Nashville, TN 37232
2 Intensive Care Nursery, Oakland Children's Hospital

In Reply.—

As indicated on p 533 of our article,1 the original recommendations given by the AMA Nutrition Advisory Group in 1975 indicated that, for premature infants, 10% of a vial should be given for each kilogram of body weight. By the time a pediatric formulation was manufactured according to the Nutrition Advisory Group guidelines, several investigators believed that 10% of a vial would not supply the needs of very low birth weight infants for vitamins A, D, and E. For this reason, an ad hoc committee was organized in 1983 by the FDA to make new recommendations for premature infants.