PEDIATRICS Vol. 80 No. 6 December 1987, pp. 946-948
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by SPRINGATE, J. E.
Right arrow Articles by FELD, L. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by SPRINGATE, J. E.
Right arrow Articles by FELD, L. G.

Acute Renal Failure in Minimal Change Nephrotic Syndrome

JAMES E. SPRINGATE MD1, JACK F. COYNE MD1, MELVYN P. KARP MD1, and LEONARD G. FELD MD, PHD1

1 Departments of Pediatrics and Pediatric Surgery School of Medicine, Children's Hospital of Buffalo, State University of New York at Buffalo

The appearance of unexplained acute renal failure during the course of idiopathic nephrotic syndrome is an uncommon but well-reported phenomenon in adults.1 Its occurrence in childhood has not been reported. We present an 8-year-old girl with minimal change nephrotic syndrome in whom inexplicable acute renal failure developed following exploratory laparotomy.

CASE REPORT

This 8-year-old girl had a 6-year history of frequently relapsing, steroid-responsive nephrotic syndrome clinically consistent with minimal change disease. While visiting the Buffalo area with her family, she suddenly had severe constant abdominal pain associated with nausea and emesis and was brought to the emergency room for evaluation. She was receiving alternate-day prednisone in an attempt to reduce the number of her relapses.