PEDIATRICS Vol. 80 No. 6 December 1987, pp. 898-903
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Renal Cell Carcinoma in Patients With Tuberous Sclerosis

Mark E. Weinblatt MD1, Ellen Kahn MD1, and Joseph Kochen MD, PhD1

1 From the Departments of Pediatrics and Pathology, Cornell University Medical College, New York; and Departments of Laboratories and Pediatrics and Division of Pediatric Hematology/Oncology, North Shore University Hospital, Manhasset, New York

An adolescent with anemia and weight loss was found to have bilateral renal cell carcinoma (hypernephroma). Further investigation revealed an underlying tuberous sclerosis that had escaped previous clinical detection. Several reports of this association were subsequently found when the world's literature was reviewed. Physicians treating patients with tuberous sclerosis should be aware of the possible development of these renal malignancies in their patients.

Key Words: renal cell carcinoma • tuberous sclerosis

Submitted on November 20, 1986
Accepted on January 19, 1987




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