PEDIATRICS Vol. 80 No. 5 November 1987, pp. 767-778
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Design and Participation

Larry S. Webber PhD1, Gail C. Frank RD, DrPH1, Carey G. Smoak MPH1, David S. Freedman PhD1, and Gerald S. Berenson MD1

1 From the Departments of Medicine and Biometry and Genetics, Louisiana State University Medical Center, New Orleans

Cardiovascular risk factor variables were examined in a cohort of 440 infants from birth through 7 years of age. Anthropometric measures, BP, serum lipid and lipoprotein values, and dietary intake data were obtained according to detailed protocols. Various quality controls to ensure the collection of valid and reliable data were instituted. Participation remained high throughout the study with 80% of the children examined at 6 months and 60% at 7 years of age. Rates were slightly higher for black than for white children. Children born in the private hospital were more likely to continue in the study than children born in the charity hospital. Children of parents examined when the child was 2 years of age were more likely to be examined during the preschool phases, but parental examination was not related to child examination when the child was 7 years of age. As in studies of school-aged children, measurement errors were lowest for height, weight, and serum total cholesterol. Measurement errors for BP were highest at the younger ages, particularly for diastolic BP. Examination of a newborn cohort throughout time affords the opportunity to study early development of relationships and tracking of cardiovascular risk factors.

Key Words: cardiovascular risk factor

Submitted on June 6, 1986
Accepted on March 30, 1987




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R. B. Jennings and S. P. Leon
Pediatric Preventive Cardiology: Experience in the Tidewater, Virginia Area
Clinical Pediatrics, February 1, 1992; 31(2): 89 - 93.
[Abstract] [PDF]