PEDIATRICS Vol. 8 No. 6 December 1951, pp. 805-813
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CASE OF ADRENOGENITAL SYNDROME WITH HYPERTENSION TREATED WITH CORTISONE

THOMAS H. SHEPARD II M.D.1 and SAMUEL W. CLAUSEN M.D.1

1 The Department of Pediatrics, the University of Rochester School of Medicine and Dentistry, Rochester, N.Y.

A 2frac12 year old patient with adrenogenital syndrome due to adrenal hyperplasia proved by biopsy and with the clinically unusual symptom of hypertension has been treated with cortisone acetate. This therapy resulted in reduction of the hypertension. The adrenogenital syndrome may be due to pituitary stimulation of the adrenal cortex. The hypertension possibly is due to compensatory zona glomerulosa changes secondary to abnormal secretion of adrenal androgens.

Submitted on June 14, 1951




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