1 From the Division of Emergency Medicine, Thomas Jefferson University Hospital, Philadelphia
A 16-month-old child who ingested rat poison, according to her parents, was noted to have signs of cholinergic poisoning. In the emergency department, the child was intubated and given atropine via the endotracheal tube until venous access was established. Phytonadione (vitamin K) and pralidoxime (2-PAM) Were also administered. The child recovered after an uneventful hospital course. The toxic agent was determined to be a carbamate insecticide, for which treatment with pralidoxime is considered controversial. Treatment of cholinergic poisoning due to unknown or mixed agents and poisoning caused by known carbamate insecticides are discussed.
Key Words: poisoning cholinesterase inhibitor pesticide insecticide carbamate
Submitted on June 13, 1986
Accepted on July 29, 1986