PEDIATRICS Vol. 79 No. 2 February 1987, pp. 315
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Neonatal Intracranial Hemorrhage and Phenobarbital

KARL C. K. KUBAN MD1, ELIZABETH BROWN MD1, ALAN LEVITON MD1, and KALPATHY KRISHNAMOORTHY MD1

1 Department of Neurology, The Children's Hospital, 300 Longwood Ave, Boston, MA 02115

In Reply.—

We appreciate the comments by Dr Battisti et al. As noted in the inclusion criteria for our study,1 all intubated babies with birth weights less than 1,751 g were eligible for the study. One of the advantages of a randomized double-blind study is that babies with other risk factors, including presence of a fluctuating cerebral blood flow pattern on Doppler ultrasound testing, should have equal chances of being in the treated and placebo groups.




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