PEDIATRICS Vol. 79 No. 2 February 1987, pp. 313
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by JAMES, H. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by JAMES, H. E.

Absent Hypoxic and Hypercapnic Arousal Responses in Children With Myelomeningocele and Apnea

HECTOR E. JAMES MD1

1 Neurosurgery and Pediatrics, University of California Medical Center, San Diego, CA

To the Editor.—

The findings by the authors of a recent report about abnormalities in hypoxic and hypercapnic arousal responses in children with myelomeningocele and Arnold-Chiari malformation, who were symptomatic with apnea and/or hyperventilation, are interesting indeed, and the abnormalities have been reported well.1

In the discussion, the authors failed to tell the readers about the known anatomical substrate for such abnormalities. The anatomical substrate is a malformation of brainstem nuclei and consequently brainstem connections of the cranial nerve nuclei and reticular formation.