PEDIATRICS Vol. 78 No. 5 November 1986, pp. 956-957
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Dyslipoproteinemia and Migraine

CHARLES J. GLUECK MD1

1 Departments of Medicine and Pediatrics, General Clinical Research, Lipid Research, and CLINFO Centers, University of Cincinnati, College of Medicine, 234 Goodman St, Cinncinnati, OH 45267-0767

In Reply.—

Because the anatomic, biochemical, epidemiologic, nutritional, genetic, and clinical genesis of atherosclerosis is in childhood,1,2 it is important to consider models for sampling in childhood for the dyslipoproteinemias. At a minimum, I would recommend a family history-triggered high-risk strategy with sampling of all children whose parents had sustained premature (leage 60 years) myocardial infarction, angina, cerebrovascular accident, or peripheral vascular disease.1,2 Second, all children with known parental dyslipoproteinemia should be sampled, as should all children with parental history of essential hypertension gout/hyperuricemia, and/or diabetes.