PEDIATRICS Vol. 78 No. 4 October 1986, pp. 692-698
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One- to Three-Year Outcome for 14 Neonatal Survivors of Extracorporeal Membrane Oxygenation

Alice French Andrews MD1, Cynthia A. Nixon RN1, Robert E. Cilley MD1, Dietrich W. Roloff MD1, and Robert H. Bartlett MD1

1 From the Departments of Pediatrics and Surgery, University of Michigan Medical Center, Ann Arbor

Extracorporeal membrane oxygenation, using venoarterial or venovenous perfusion, is a safe and effective procedure in the term or near-term infant with life-threatening respiratory failure. Without extracorporeal membrane oxygenation, due to the severity of their disease, these children are at high risk for neurologic damage, chronic lung disease, and death. Because survival is not expected without extracorporeal membrane oxygenation therapy, there is no corresponding control group to which these survivors may be compared. In this report, we reviewed the outcome at 1 to 3 years in the first 14 survivors of extracorporeal membrane oxygenation treated at our institution. Seven of 14 neonatal extracorporeal membrane oxygenation survivors (50%) were normal or near normal at between 1 and 3 years of age. Ten (71%) had normal mental ability. We conclude that in neonates with high mortality risk from respiratory failure, near-normal growth and development can be expected in the majority who survive with extracorporeal membrane oxygenation treatment.

Key Words: extracorporeal membrane oxygenation • neonate

Submitted on December 16, 1985
Accepted on June 4, 1986




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