PEDIATRICS Vol. 78 No. 3 September 1986, pp. 516-518
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Prospective Diagnosis of Pseudohypoaldosteronism

ALAN M. SCHINDLER MD1 and GARRETT E. BERGMAN MD1

1 Department of Pediatrics, The Medical College of Pennsylvania, Philadelphia

Pseudohypoaldosteronism is characterized by salt wasting in spite of elevated plasma renin activity and serum aldosterone concentration. If the salt wasting is severe, pseudohypoaldosteronism may present as early as the first or second week of life. We were able to demonstrate pseudohypoaldosteronism on the second day of life in an asymptomatic newborn baby whose father and 1-year-old sister were known to have pseudohypoaldosteronism.

CASE REPORTS

Case 1

The patient was a 6-week-old white girl, who was born at term. Her mother was 24 years old, primigravida, and had an uncomplicated pregnancy. The baby was admitted to the hospital for evaluation of lethargy, poor feeding, vomiting, and failure to thrive when fed breast milk and, later, a proprietary formula.




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P. M. Mathew, K. B. Manasra, and J. A. Hamdan
Indomethacin and Cation-Exchange Resin in The Management of Pseudohypoaldosteronism
Clinical Pediatrics, January 1, 1993; 32(1): 58 - 60.
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