PEDIATRICS Vol. 77 No. 2 February 1986, pp. 242-245
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Dynamics of Nasopharyngeal Colonization With Haemophilus influenzae b During Antibiotic Therapy

JANET R. GILSDORF MD1

1 C. S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor

Haemophilus influenzae type b, a major cause of serious infections in infants and young children, may colonize the nasopharynges of healthy, asymptomatic carriers as well as patients with invasive H influenzae type b disease. Person to person spread of this organism is suspected to be by infected respiratory tract secretions. Recently, clusters of epidemiologically related cases have been recognized among young household and day-care contacts of children with H influenzae type b disease,1 demonstrating the contagious potential of H influenzae type b infections.

Serious nosocomial infections with H influenzae type b have been described in pediatric patients in acute and chronic care hospitals.2-4


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