PEDIATRICS Vol. 76 No. 6 December 1985, pp. 981-984
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Infantile Myofibromatosis

THOMAS E. WISWELL MC, USA1, E. LAWRENCE SAKAS MC, USA1, STEPHEN R. STEPHENSON MC, USA1, JOHN J. LESICA MC, USA1, and SHIRLEY R. REDDOCH MC, USA1

1 Departments of Pediatrics and Pathology, Tripler Army Medical Center, Honolulu

We recently cared for an infant with infantile myofibromatosis, a rare condition involving the dermal, visceral, musculoskeletal, and subcutaneous tissues. Most reports of this disorder have appeared in the pathology, cancer, and radiology literature.1-7 We report this case and review this condition in order to familiarize pediatricians with the clinical manifestations, histopathologic features, and prognosis of affected infants.

CASE REPORT

A 2,970-g female infant was born at term to a gravida 2, para 1 woman following an uncomplicated pregnancy. The family history was unremarkable. The infant's initial physical examination revealed a raised, hard, violaceous mass on the left side of the face, measuring 4 x 5 cm and extending from the upper lip to the lower eyelid and involving the nose (Fig 1).




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