1 Departments of Pediatrics and Neurology, University of Michigan Medical Center, Ann Arbor
Lithium is commonly used to treat bipolar depression in adults. Several recent studies demonstrate the efficacy of the drug for certain behavioral and affective disorders in children.1 There is also evidence that lithium may be therapeutic in a diverse group of clinical problems including premenstrual syndrome, neutropenia, cluster headaches, certain movement disorders, and syndrome of inappropriate antidiuretic hormone secretion.2-6 Thus, it appears that lithium use will increase, resulting in its greater availability for accidental poisoning. Currently, this is a rare event. A recent literature review disclosed no reports of single-dose intoxications either in childhood or manifesting as dystonia. The following is a description of a child who presented with dystonia associated with lithium ingestion.