PEDIATRICS Vol. 76 No. 5 November 1985, pp. 725-733
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sauve, R. S.
Right arrow Articles by Singhal, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sauve, R. S.
Right arrow Articles by Singhal, N.

Long-Term Morbidity of Infants With Bronchopulmonary Dysplasia

Reg S. Sauve MD, MPH, FRCP(C)1 and Nalini Singhal MD, FRCP(C)1

1 From the Department of Community Health Sciences, Faculty of Medicine, The University of Calgary, Calgary, Alberta, Canada

Bronchopulmonary dysplasia occurred in 179 infants discharged from a regional neonatal intensive care unit between 1975 and 1982. Perinatal and outcome factors were compared for these study infants and a group of 112 controls matched for birth weight category and year of birth. There were multiple differences between study infants and controls in demographic, diagnostic, and therapeutic items, all of which were categorized as pulmonary items occurring before and after the development of bronchopulmonary dysplasia, and nonpulmonary items. The postdischarge death rate was 11.2% in infants and 0.9% in control infants (P < .001). Ongoing morbidity was most marked in the areas of health history, physical examination, growth, and vision. Neurodevelopmental abnormalities and hearing abnormalities occurred slightly more frequently in study infants than in controls but not significantly so. Major developmental abnormalities were less frequent in this population than has been the case in other follow-up studies in this area. This group of infants requires close postdischarge observation because ongoing morbidity and postdischarge mortality, part of which may be preventable, are frequent.

Key Words: bronchopulmonary dysplasia • morbidity

Submitted on December 26, 1984
Accepted on March 26, 1985




This article has been cited by other articles:


Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
D Ari-Even Roth, M Hildesheimer, A Maayan-Metzger, C Muchnik, A Hamburger, R Mazkeret, and J Kuint
Low prevalence of hearing impairment among very low birthweight infants as detected by universal neonatal hearing screening
Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2006; 91(4): F257 - F262.
[Abstract] [Full Text] [PDF]

Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
D J Henderson-Smart, J L Hutchinson, D A Donoghue, N J Evans, J M Simpson, I Wright, and for the Australian and New Zealand Neonatal Networ
Prenatal predictors of chronic lung disease in very preterm infants
Arch. Dis. Child. Fetal Neonatal Ed., January 1, 2006; 91(1): F40 - F45.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
R. A. K. Jones and on behalf of the Collaborative Dexamethasone Trial
Randomized, Controlled Trial of Dexamethasone in Neonatal Chronic Lung Disease: 13- to 17-Year Follow-up Study: I. Neurologic, Psychological, and Educational Outcomes
Pediatrics, August 1, 2005; 116(2): 370 - 378.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
S. J. Gross, R. D. Anbar, and B. B. Mettelman
Follow-up at 15 Years of Preterm Infants From a Controlled Trial of Moderately Early Dexamethasone for the Prevention of Chronic Lung Disease
Pediatrics, March 1, 2005; 115(3): 681 - 687.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
L. M. Askie, D. J. Henderson-Smart, L. Irwig, and J. M. Simpson
Oxygen-Saturation Targets and Outcomes in Extremely Preterm Infants
N. Engl. J. Med., September 4, 2003; 349(10): 959 - 967.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
Statement on the Care of the Child with Chronic Lung Disease of Infancy and Childhood
Am. J. Respir. Crit. Care Med., August 1, 2003; 168(3): 356 - 396.
[Full Text] [PDF]

Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
M W Beresford, R Primhak, N V Subhedar, and N J Shaw
Randomised double blind placebo controlled trial of inhaled fluticasone propionate in infants with chronic lung disease
Arch. Dis. Child. Fetal Neonatal Ed., July 1, 2002; 87(1): F62 - 63.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
M.-C. Gregoire, F. Lefebvre, and J. Glorieux
Health and Developmental Outcomes at 18 Months in Very Preterm Infants With Bronchopulmonary Dysplasia
Pediatrics, May 1, 1998; 101(5): 856 - 860.
[Abstract] [Full Text] [PDF]

Home page
 J Learn DisabilHome page
A. M. Farel, S. R. Hooper, S. W. Teplin, M. M. Henry, and E. N. Kraybill
Very-Low-Birthweight Infants at Seven Years: An Assessment of the Health and Neurodevelopmental Risk Conveyed by Chronic Lung Disease
J Learn Disabil, March 1, 1998; 31(2): 118 - 126.
[Abstract] [PDF]

Home page
 PediatricsHome page
S. A. Nachman, M. Navaie-Waliser, and M. Z. Qureshi
Rehospitalization With Respiratory Syncytial Virus After Neonatal Intensive Care Unit Discharge: A 3-Year Follow-up
Pediatrics, December 1, 1997; 100(6): e8 - e8.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
L. Singer, T. Yamashita, L. Lilien, M. Collin, and J. Baley
A Longitudinal Study of Developmental Outcome of Infants With Bronchopulmonary Dysplasia and Very Low Birth Weight
Pediatrics, December 1, 1997; 100(6): 987 - 993.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
T. Bhuta and D. J. Henderson-Smart
Elective High-frequency Oscillatory Ventilation Versus Conventional Ventilation in Preterm Infants With Pulmonary Dysfunction: Systematic Review and Meta-analyses
Pediatrics, November 1, 1997; 100(5): e6 - e6.
[Abstract] [Full Text] [PDF]

Home page
 CLIN PEDIATRHome page
R.S. Sauve, D.D. McMillan, I. Mitchell, D. Creighton, N.W. Hindle, and L. Young
Home Oxygen Therapy: outcome of Infants Discharged from NICU on Continuous Treatment
Clinical Pediatrics, March 1, 1989; 28(3): 113 - 118.
[Abstract] [PDF]