PEDIATRICS Vol. 76 No. 4 October 1985, pp. 518-523
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Risk Factors for Measles Vaccine Failure Among Immunized Students

Harry F. Hull MD1, Jean M. Montes BA1, Patricia C. Hays BS1, and Robert L. Lucero MPA1

1 From the New Mexico Health and Environmental Department, Santa Fe

An outbreak of measles occurred in a municipal school system which had reported 98% of students immunized against measles. A case-control study was conducted to determine reasons for vaccine failure Vaccine failure was associated with immunizations that could not be documented in the provider's records. Among children with provider-documented immunization, vaccine failure was associated with vaccination at 12 to 14 months of age with an odds ratio of 4.73. Among children vaccinated at 15 months or older, vaccine failure was not associated with time elapsed since vaccination. Studies should be conducted to determine whether unreliable immunization records are a more widespread problem. Further consideration should be given to routine revaccination of children previously vaccinated at 12 to 14 months of age.

Key Words: measles • vaccine failure • immunization

Submitted on February 6, 1985
Accepted on February 22, 1985




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[Abstract] [Full Text]