PEDIATRICS Vol. 76 No. 2 August 1985, pp. 202-205
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Reye Syndrome Associated with Aspirin Therapy for Systemic Lupus Erythematosus

James R. Hansen MD1, Paul B. McCray MD1, James F. Bale Jr MD1, Austin J. Corbett MD1, and David J. Flanders MD1

1 From the Departments of Pediatrics, Neurology, Internal Medicine, and Pathology, University of Iowa College of Medicine, Iowa City

A 14-year-old girl in whom Reye syndrome developed during aspirin therapy for an inflammatory disorder proven to be systemic lupus erthymatosus is reported. This case and similar cases of Reye syndrome in patients with juvenile rheumatoid arthritis suggest that an etiologic relationship exists between salicylate therapy and Reye syndrome in children with collagen vascular disorders.

Key Words: Reye syndrome • systemic lupus erthymatosus • salicylism

Submitted on June 25, 1984
Accepted on August 22, 1984




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