PEDIATRICS Vol. 75 No. 6 June 1985, pp. 1170-1171
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In Reply: White Blood Cell Transfusions

MITCHELL S. CAIRO MD1

1 Childrens Hospital of Orange County, 1109 W LaVeta Ave, Orange, CA 92668

The first question concerning the ratio of suspected to proven neonatal sepsis is a good one. Our ratio was so low because of the strict clinical criteria that we adhered to for patient entry into study. Because we are a tertiary children's hospital and do not have an obstetrical unit attached to our institution, most patients referred to our institution are very critically ill. In our area, the vast majority of neonates for whom sepsis is ruled out are being taken care of at intermediate centers, and I agree that most of the ratios of suspected to proven neonatal sepsis are probably quite high in those centers.