PEDIATRICS Vol. 75 No. 5 May 1985, pp. 904-907
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Concurrent Agenesis of the Corpus Callosum and Ureteroceles in Siblings

AVE M. LACHIEWICZ MD1, STANLEY J. KOGAN MD1, SELWYN B. LEVITT MD1, and RICHARD L. WEINER MD1

1 Department of Pediatrics and Division of Pediatric Urology, The Hospital of the Albert Einstein College of Medicine, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York

Agenesis of the corpus callosum is an uncommon anomaly that exists in complete and partial forms. It has been associated with other cerebral malformations as well as facial, genitourinary, musculoskeletal, cardiac, and respiratory anomalies.1 Agenesis of the corpus callosum is generally sporadic but it has been reported in several families.2 Ureteroceles frequently occur in association with duplications of the ureters.3 The hereditary occurrence of ureteroceles has been reported in five families.4-8 In this report, we describe two brothers with the simultaneous occurrence of agenesis of the corpus callosum and orthotopic ureteroceles.

Two brothers were seen at The Hospital of the Albert Einstein College of Medicine for evaluation of urologic abnormalities.