PEDIATRICS Vol. 75 No. 4 April 1985, pp. 672-675
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Progressive Varicella in Three Patients with Wiskott-Aldrich Syndrome: Treatment with Adenine Arabinoside

Nancy A. Wade MD1, Martha L. Lepow MD1, James Veazey MD1, and Hilaire J. Meuwissen MD1

1 From the Department of Pediatrics, Albany Medical College; Birth Defects Institute, Center for Laboratories and Research, New York State Department of Health; and Clinical Studies Center, Albany Medical College, Albany, New York

Patients with Wiskott-Aldrich Syndrome have an increased incidence of serious infections, often with microorganisms that usually produce mild disease in immunologically normal subjects. Three patients with Wiskott-Aldrich syndrome complicated by progressive varicella are reported. There have been no previous reports of similar cases. Two of the patients were treated with adenine arabinoside and had rapid recovery.

Key Words: progressive varicella • Wiskott-Aldrich syndrome • adenine arabinoside

Submitted on December 30, 1983
Accepted on April 24, 1984




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