PEDIATRICS Vol. 75 No. 2 February 1985, pp. 372-373
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Vitamin K Deficiency

ARTURO J. ABALLI MD1

1 Miami Children's Hospital, 6125 Southwest 31st St, Miami, FL 33155

To the Editor.—

The article by Payne and Hasegawa1 on vitamin K deficiency of the newborn correctly stresses the existence of differences between vitamin K deficiency and Coumadin effect. This has been somewhat forgotten in important studies on the mode of action of prothrombin.2-4 Modern techniques as the Echis time5 and certain sophisticated electrophoretic6 methods confirm the suspected differences between these two disorders. However, many years ago it was shown7-9 that microgram doses of any vitamin K rapidly corrected the coagulation defect in deficiency.