PEDIATRICS Vol. 75 No. 1 January 1985, pp. 142-145
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Significance of Growth Modulators in Human Milk

Gerald E. Gaull MD1, Charles E. Wright PhD1, and Charles E. Isaacs PhD1

1 From the Department of Human Development and Nutrition, Institute for Basic Research in Developmental Disabilities, Staten Island, New York

Human milk contains growth modulators of potential clinical importance to the neonate. Evidence from animal and cell culture models as well as ancillary evidence about their stability and the way some of them are processed for secretion suggest they are probably physiologically significant. Their presence in human milk does not by itself establish their importance; however, it is useful to explore their potential functional roles. Growth modulators present in human milk include: EGF, NGF, certain enzymes, and taurine.

Key Words: epidermal growth factor • human milk enzymes • nerve growth factor • taurine




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