PEDIATRICS Vol. 74 No. 5 November 1984, pp. 898
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Zinc and Low Birth Weight: Relationship Questioned

UGO CARPENTIERI MD, ScD1, C. W. DAESCHNER III MD1, LEIGH R. SMITH JR MD1, and MARY ELLEN HAGGARD MD1

1 Department of Pediatrics, University of Texas Medical Branch, Galveston, TX 77550

To the Editor.—

Kumar and Anday1 recommended the addition of zinc deficiency to the list of causes of generalized edema in low-birth-weight infants.

In our opinion, none of the three patients they described support this conclusion, although the conclusion itself may be true. One patient, in fact, improved with protein supplementation alone, although over a longer period of time, and the other two patients improved with protein and zinc supplementation over a period of four to five days.