PEDIATRICS Vol. 73 No. 4 April 1984, pp. 530-531
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Recurrence of Rheumatic Fever During Prophylaxis with Monthly Benzathine Penicillin G

James D. Nordin MD, MPH1

1 From St Paul, Minnesota

A 9-year-old girl had apparent recurrence of rheumatic fever while receiving monthly benzathine penicillin injections. A review of pharmacokinetc studies on the subject suggests that this is a real risk. A need for review of the current recommendations for rheumatic fever prophylaxis is suggested.

Key Words: rheumatic fever • prophylaxis failure

Submitted on May 16, 1983
Accepted on August 8, 1983