PEDIATRICS Vol. 73 No. 4 April 1984, pp. 502-506
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The Melkersson-Rosenthal Syndrome

William B. Wadlington MD1, Harris D. Riley Jr MD1, and Leo Lowbeer MD1

1 From the Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee; Department of Pediatrics and Children's Memorial Hospital, University of Oklahoma Health Sciences Center, Oklahoma City; and Department of Pathology, Hillcrest Medical Center, Tulsa, Oklahoma

The Melkersson-Rosenthal syndrome consists of recurrent swelling of the lip or face, intermittent facial palsy, and fissured tongue. Lengthy intervals may occur between those various manifestations. Four white female patients with this disorder are described. First identified in Europe, the condition is now increasingly recognized in this country. The cause is unknown. The pathology, clinical features, and management of this unusual disorder are discussed.

Key Words: Melkersson-Rosenthal syndrome • facial swelling • facial paralysis

Submitted on February 14, 1983
Accepted on May 20, 1983


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