PEDIATRICS Vol. 73 No. 2 February 1984, pp. 194-198
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A Cluster of Neonatal Herpes Simplex Infections Without Mucocutaneous Manifestations

Antonio J. Amortegui MD1, Trevor A. Macpherson MB, ChB, MRCOG.1, and James H. Harger MD1

1 From the Departments of Pathology, and Obstetrics and Gynecology, University of Pittsburgh School of Medicine, Magee-Womens Hospital, Pittsburgh

Three cases of neonatal disseminated herpes simplex virus (HSV) infection are reported. They were all due to different strains of HSV-1, according to restriction endonuclease studies, and they represent the first cluster of neonatal HSV infection at Magee-Womens Hospital. The neonatal symptoms occurred early, suggesting intrauterine infection. None of the babies had mucocutaneous lesions, and the mothers were asymptomatic and had no history of previous genital HSV infection.

Key Words: neonatal death • herpes simplex • neonatal infection

Submitted on January 10, 1983
Accepted on May 4, 1983