PEDIATRICS Vol. 72 No. 6 December 1983, pp. 872-876
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Use of Extracorporeal Membrane Oxygenation for Respiratory Failure in Term Infants

Barry V. Kirkpatrick MD1, Thomas M. Krummel MD1, Dawn G. Mueller MD1, Miguel A. Ormazabal MD1, Lazar J. Greenfield MD1, Arnold M. Salzberg MD1, Stephen L. Crute BS1, and Peter A. Boswell BS1

1 From the Department of Pediatrics/Children's Medical Center, and Department of Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond

Eight infants with intractable respiratory failure were treated with extracorporeal membrane oxygenation. Intractable respiratory failure was defined as alveolar-arterial oxygen gradient of more than 620 torr for six to 12 hours that did not respond to hyperventilation and the use of tolazoline. Infants with overt sepsis, CNS damage, or other debilitating conditions were not considered for extracorporeal membrane oxygenation. Six of the eight infants survived after a mean extracorporeal membrane oxygenation time of 164 hours. Five of the six survivors were normal neurologically and developmentally when examined at 1 year of age.

Key Words: respiratory failure • extracorporeal membrane oxygenation

Submitted on October 11, 1982
Accepted on March 8, 1983




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