PEDIATRICS Vol. 72 No. 6 December 1983, pp. 828-830
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Parish, R. A.
Right arrow Articles by Burns, R. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Parish, R. A.
Right arrow Articles by Burns, R. M.

Interaction of Theophylline with Erythromycin Base in a Patient with Seizure Activity

Ruth Ann Parish MD1, N. Jean Haulman MD1, and Robert M. Burns MD1

1 From the Department of Pediatrics, Division of Ambulatory Pediatrics, University of Washington School of Medicine, Harborview Medical Center, and Children's Orthopedic Hospital and Medical Center, Seattle

A pediatric patient who was taking carefully monitored doses of theophylline for chronic asthma, was placed on erythromycin base for bronchitis. She subsequently developed theophylline toxicity which caused her to experience seizure activity. Any patient taking a theophylline preparation who is then placed on ANY of the available erythromycin compounds must have close monitoring of serum theophylline levels.

Key Words: theophylline • erythromycin base • asthmatic children • drug interactions • drug toxicity

Submitted on December 28, 1982
Accepted on February 15, 1983