PEDIATRICS Vol. 72 No. 5 November 1983, pp. 724-730
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Cardiac Complications in Children with Systemic Lupus Erythematosus

Janet A. Englund MD1 and Russell V. Lucas Jr MD1

1 From Pediatric Grandest Rounds, Edward L. Kaplan, MD, Coordinator, University of Minnesota, Minneapolis

Two patients had cardiac complications of childhood onset systemic lupus erythematosus (SLE). A 14-year-old boy had extramural and intramural coronary arteritis demonstrated by angiography. The signs and symptoms of myocardial ischemia improved dramatically when corticosteroid dose and immunosuppression were increased. A 20-year-old woman had had SLE for 18 years and had functionally significant mitral stenosis and regurgitation. Calcification of the mitral valve was observed on echocardiography. Corticosteroid treatment has controlled the renal manifestations of SLE. Cardiac complications of SLE are now a significant clinical problems.

Key Words: systemic lupus erythematosus • Libman-Sacks endocarditis • coronary arteritis • mitral stenosis • coronary atherosclerosis

Submitted on November 29, 1982
Accepted on March 3, 1983




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A. H. Matayoshi, M. R. Dhond, and L. J. Laslett
Multiple Coronary Aneurysms in a Case of Systemic Lupus Erythematosus
Chest, October 1, 1999; 116(4): 1116 - 1118.
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