PEDIATRICS Vol. 72 No. 3 September 1983, pp. 405-407
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Differences in Polymorphonuclear Cell Counts Between Healthy White and Black Infants: Response to Meningitis

P. David Sadowitz MD1 and Frank A. Oski MD1

1 From the Department of Pediatrics, State University of New York, Upstate Medical Center, Syracuse

Both black adults and black children have significantly lower total WBC counts and absolute polymorphonuclear WBC counts than do white adults and white children. In an effort to determine whether similar differences existed in infancy, 50 healthy black infants and 50 white infants were examined. The black infants, 9 to 12 months of age, were found to have significantly lower total WBC counts, absolute neutrophil counts, and absolute lymphocyte counts. In ten of the 50 black infants, the absolute neutrophil counts were less than 1,000/µL; none of the white infants had absolute neutrophil counts of less than 1,000/µL. Even in the presence of a serious infection, meningitis, significantly fewer black infants had absolute neutrophil counts greater than 10,000/µL than did their white counterparts.

Key Words: leukocytes • healthy infants • meningitis

Submitted on October 20, 1982
Accepted on November 30, 1982




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