PEDIATRICS Vol. 72 No. 3 September 1983, pp. 300-306
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Factors Associated with Infections Among Breast-Fed Babies and Babies Fed Proprietary Milks

Grace E. Holmes MD1, Khatab M. Hassanein PhD1, and Herbert C. Miller MD1

1 From the Departments of Pediatrics, Community Health, and Biometry, University of Kansas Medical Center, College of Health Sciences and Hospital, Kansas City

Correlation of first postnatal year infections among 251 babies was made with the infant feeding mode, socioeconomic status of family, maternal educational level, age, and maternal behavioral factors including smoking habit and number of siblings in the family. Initially, 127 mothers intended to breast-feed and 124 intended to formula-feed their infants. In the correlation matrix maternal education was the highest variable inversely correlated with infection; it was the first to enter in stepwise regression analysis and was highly significant (P <.0001). Maternal weight gain during pregnancy and infant feeding mode were the next two variables, respectively, to be added during the stepwise regression but they were not significant in the presence of maternal education. The statistical significance of increased maternal education in inverse relation to infection persisted in the presence of the other two factors (P <.0064). The t test showed no significant difference in the number of infections among the breast-fed and formula-fed babies within any of the three maternal education groups. It may be concluded that in the population studied, the infant feeding mode itself was not significantly related to the number of infections during the infant's first postnatal year when the education of the mother was taken into account.

Key Words: breast-feeding • milk formula • morbidity • infection • maternal education

Submitted on August 9, 1982
Accepted on December 29, 1982




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K. G. Auerbach, M. J. Renfrew, and M. Minchin
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J Hum Lact, June 1, 1991; 7(2): 63 - 71.
[Abstract] [PDF]