PEDIATRICS Vol. 72 No. 1 July 1983, pp. 143-144
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Plasma Threonine in Premature Infants

NIELS RÄIHÄ MD1, DAVID RASSIN PHD2, and GERALD GAULL MD3

1 Department of Pediatrics, University of Lund, Malmö General Hospital, S-214 01 Malmö, Sweden
2 Division of Developmental Nutrition, and Metabolism, Department of Pediatrics, University of Texas Medical Branch, Galveston, TX 77550
3 Department of Human Development and Nutrition, New York State Institute for Basic, Research in Developmental Disabilities, Staten Island, NY 10314

In Reply.—

The major point raised by the letter of Rigo and Senterre is that the plasma threonine concentration should decrease with increasing gestational age in the groups with high threonine intake (>1,500 µmol/kg/day). These are the infants receiving a milk formula containing 3.0 g/100 mL of protein in one of our first studies.1 In our recent study on term infants2 the threonine intake in the formula-fed infants was <1,500 µmol/kg/day. Plasma threonine values in relation to gestational age from the first study are shown in the Table.