PEDIATRICS Vol. 71 No. 3 March 1983, pp. 337-341
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Superior Vena Cava Syndrome in Childhood: Report of Ten Cases and Review of the Literature

Philip Y. Issa MD1, Emile R. Brihi MD1, Yves Janin MD1, and Michel S. Slim MD, FAAP1

1 From the Departments of Radiotherapy and Surgery, American University Medical Center, Beirut, Lebanon

Experience with ten children with superior vena cava obstruction is reported. Five patients had non-Hodgkin's lymphoma, two had Hodgkin's disease, two had benign lesions, and one patient was suspected on clinical and radiologic basis to have a lymphoma. The clinical situation at presentation was often critical and required rapid treatment. Radiotherapy and/or chemotherapy were used initially as lymphoma was the most frequent cause of obstruction. Urgent thoracotomy was resorted to when treatment failed. Survival with no evidence of disease for more than 5 years was observed in three children: one had a cystic lymphangioma, another had a mediastinal abscess, and the third had a Hodgkin's lymphoma. Review of the literature from 1951 to 1976 revealed that only 24/150 children reported with superior vena cava obstruction syndrome had mediastinal tumors; the remainder developed the obstruction after surgical procedures on the heart or vena cava.

Key Words: superior vena cava • staphylococcal abscess • cystic hygroma • mediastinal lymphoma

Submitted on February 19, 1981
Accepted on June 3, 1982




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