PEDIATRICS Vol. 70 No. 6 December 1982, pp. 976-978
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Acquired Postganglionic Cholinergic Dysautonomia: Case Report and Review of the Literature

Sarla Inamdar MD1, Lon B. Easton MD1, and Georgina Lester MD1

1 The Department of Pediatrics, New York Medical College-Metropolitan Hospital Center, New York

An 8-year-old girl with acute abdominal pain had cholinergic autonomic dysfunction. There have been only four patients with acquired postganglionic cholinergic dysautonomia described in the literature. The characteristic clinical features are atony of the bowel and bladder, lack of tears, saliva, and sweat, internal ophthalmoplegia, and normal adrenergic functions. Special studies for autonomic nervous function help in confirming this diagnosis. The exact pathogenesis of the disorder is still not clear. This case demonstrates successful treatment with bethanechol chloride.

Key Words: acquired postganglionic cholinergic dysautonomia • acquired dysautonomia • acute autonomic neuropathy • cholinergic dysfunction

Submitted on November 18, 1981
Accepted on December 31, 1981