PEDIATRICS Vol. 70 No. 6 December 1982, pp. 931-934
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Golden, N. L.
Right arrow Articles by Bottoms, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Golden, N. L.
Right arrow Articles by Bottoms, S.

Maternal Alcohol Use and Infant Development

Nancy L. Golden MD1, Robert J. Sokol MD1, Betty R. Kuhnert PhD1, and Sidney Bottoms MD1

1 The Departments of Pediatrics, Obstetrics and Gynecology and Perinatal Clinical Research Center, Cleveland Metropolitan General Hospital/Case Western Reserve University, Cleveland

A prospective controlled study of the effect of fetal alcohol on infant development was performed. Twelve infants were identified as possibly having fetal alcohol effects based on the maternal history of alcohol abuse and the neonatal physical examination. Physical characteristics, growth, and development of these infants were compared with those of 12 control infants at birth and at a mean age of 12 months; control infants were matched for gestational age, sex, and race. Data were evaluated by descriptive statistics and analysis of differences between matched pairs of study and control infants. The results showed a significant correlation between the history of heavy antenatal maternal alcohol use and delayed mental and motor development, physical abnormalities, and growth retardation in the infants. This study suggests that infants with fetal alcohol effects can be correctly classified at birth and their outcome accurately predicted.

Key Words: alcohol • development • growth retardation

Submitted on December 7, 1981
Accepted on March 23, 1982




This article has been cited by other articles:


Home page
 Drug Metab. Dispos.Home page
D. G. McCarver
ADH2 and CYP2E1 Genetic Polymorphisms: Risk Factors for Alcohol-Related Birth Defects
Drug Metab. Dispos., April 1, 2001; 29(4): 562 - 565.
[Abstract] [Full Text]

Home page
 J. Pharmacol. Exp. Ther.Home page
D. G. McCarver, H. R. Thomasson, S. S. Martier, R. J. Sokol, and T.-K. Li
Alcohol Dehydrogenase-2*3 Allele Protects Against Alcohol-Related Birth Defects Among African Americans
J. Pharmacol. Exp. Ther., December 1, 1997; 283(3): 1095 - 1101.
[Abstract] [Full Text]