PEDIATRICS Vol. 70 No. 6 December 1982, pp. 1013
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Cerebral Blood Flow

BARRY G. BAYLEN MD1 and GEORGE C. EMMANOUILIDES MD1

1 Division of Pediatric Cardiology, Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093

In the commentary, "Pulsatility Index, Patent Ductus Arteriosus, and Brain Damage," It was stated that we have shown that "blood flow" to the brain was not reduced in premature lambs with left-right ductal shunting. The abstracted data referred primarily to alteration of the percent distribution of blood flow and not to changes of absolute blood flow to systemic organs before and after patent ductus arteriosus (PDA) occlusion in preterm lambs. We subsequently demonstrated that absolute cerebral blood flow (milliliters per gram per minute) in fact was significantly reduced in preterm lambs with PDA.