PEDIATRICS Vol. 70 No. 4 October 1982, pp. 661
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Letter to the Editor

Andrew W. Zimmerman MD1

1 Departments of Neurology and Pediatrics, The University of Connecticut Health Center, Farmington, CT 06032

Tasic and colleagues are correct in pointing out the potential hazards of zinc toxicity in treating infants with acrodermatitis due to low zinc in their mothers' milk. Infants, especially premature infants, who have symptoms of acrodermatitis enteropathica while being breast-fed should be assumed to have normal capacity for uptake of zinc in the gut. If breast-feeding is continued during administration of zinc, the plasma zinc level can be expected to rise rapidly. This is due in part to the positive effect of human breast milk on zinc absorption as well as normal absorptive capacity.


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