PEDIATRICS Vol. 7 No. 5 May 1951, pp. 623-626
This Article
Right arrow Full Text (PDF)
Right arrow P3Rs: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when P3Rs are posted
Right arrow Alert me if a correction is posted
Services
Right arrow E-mail this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by KERPEL-FRONIUS, E.
Right arrow Articles by KUN, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by KERPEL-FRONIUS, E.
Right arrow Articles by KUN, K.

RELATION OF O2 CONSUMPTION TO CIRCULATION IN DIFFERENT STAGES OF INFANTILE MALNUTRITION

E. KERPEL-FRONIUS M.D.1, F. VARGA M.D.1, J. VÖNÖCZKY M.D.1, and K. KUN M.D.1

1 The Department of Pediatrics, University of Pécs, Pécs, Hungary.

The relation of O2 consumption to circulation was studied in varying stages of infantile malnutrition. In severe "dystrophy" O2 consumption and circulation are somewhat increased. In severe "atrophy" both cardiac output and O2 consumption fall to lower values, the lowered metabolic need of the tissues, however, being met by even a slower circulation. The condition is similar to that found in hypothyreotic patients. In athrepsia circulation collapses far below the metabolic need of the wasted organism; anoxia of the stagnating type ensues. Anoxia is, however, milder than in severe anhydremic circulatory shock, because the metabolic need of the tissues has decreased during the long atrophic and inanition period that preceded the terminal, athreptic stage of malnutrition. The poor circulation of the severely marantic infant may be an important factor in the high mortality rate when such patients suffer intercurrent infections, especially in pneumonia and diarrheal disease.