PEDIATRICS Vol. 69 No. 4 April 1982, pp. 466-471
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Evaluation of a Commercial Latex Particle Agglutination Test for Rapid Diagnosis of Haemophilus influenzae Type b Infection

Robert S. Daum MD, CM1, George R. Siber MD, CM1, Jill S. Kamon MD1, and Rebecca R. Russell MD1

1 Department of Pediatrics, Tulane University School of Medicine, New Orleans, and The Sidney Farber Cancer Institute, Boston

The effectiveness of a commercially available latex particle agglutination test (Bactogen) in the diagnosis of invasive Haemophilus influenzae type b infection was evaluated. Bactogen correctly diagnosed all 27 patients with bacteriologically proven H influenzae type b infection (sensitivity 100%). Two of 39 patients with proven, non-H influenzae type b infections had false-postive tests (specificity 95%). One of 103 sera and 0 of 55 urine specimens from hospitalized adults contained detectable H influenzae type b antigen. Bactogen is a sensitive, specific, commercially available test for rapid diagnosis of H influenzae type b infection.

Submitted on May 4, 1981
Accepted on June 17, 1981


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M. I. Marks
Haemophilus influenzae Infections: The Impact of Resistance on the Use of Aminopenicillins and Other Antimicrobials in Outpatient Therapy
Clinical Pediatrics, October 1, 1984; 23(10): 535 - 541.
[Abstract] [PDF]