PEDIATRICS Vol. 68 No. 4 October 1981, pp. 534-538
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Cefuroxime Therapy of Gonorrhea and Coinfection with Chlamydia trachomatis in Children

Pisespong Patamasucon MD1, Philip J. Rettig MD1, and John D. Nelson MD1

1 Department of Pediatrics, The University of Texas Health Science Center at Dallas, Southwestern Medical School, Dallas

Twenty-seven episodes of gonorrhea occurring in children less than 15 years of age were treated with an intramuscular injection of cefuroxime, 25 mg/kg. Gonococci were eliminated from genital, pharyngeal, and anal sites in all cases. Cefuroxime was well tolerated and no side effects were observed. Coinfection with Chiamydia trachomatis was found in nine patients (33%). Among the seven patients with chiamydial genital infection, postgonococcal symptoms persisted in three children (43%). One patient ofthe five with chlamydial anal infection had symptoms. Chlamydial infections were successfully treated with trisulfapyrimidines.

Submitted on December 5, 1980
Accepted on January 16, 1981