Gastroesophageal Reflux-Associated Recurrent Pneumonia and Chronic Asthma in Children
1 Department of Pediatrics, and Divisions of Pediatric Gastroenterology, Surgery, and Allergy/Immunology, UCLA Medical Center, Los Angeles
Forty of 82 patients with recurrent pneumonias and/or clinical asthma were found to have gastroesophageal reflux (GER) by the criteria of two or more of five tests positive for GER. Of 36 patients with GER followed for response to therapy, 32 patients attempted medical therapy and four had fundoplications. Ten of 32 (31%) patients on medical therapy had improvement in symptoms but none became asymptomatic. Twenty patients who failed a trial of medical therapy also had fundoplications for a total of 24 patients surgically treated. Of these, 22 (92%) had improvement or became asymptomatic. All seven patients with diagnosed GER and recurrent pneumonias responded to medical antireflux management or fundoplication. GER is an important treatable cause of recurrent pneumonias and/or chronic asthma in children.
Submitted on May 20, 1980Accepted on November 12, 1980
CiteULike 
Connotea 
Del.icio.us 
Digg 
Facebook 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  S. Michail Gastroesophageal Reflux Pediatr. Rev., March 1, 2007; 28(3): 101 - 110. [Full Text] [PDF]
|
|
|
|
 |
|
 A. B. Goldin, R. Sawin, K. D. Seidel, and D. R. Flum Do Antireflux Operations Decrease the Rate of Reflux-Related Hospitalizations in Children? Pediatrics, December 1, 2006; 118(6): 2326 - 2333. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. P. Boesch, C. Daines, J. P. Willging, A. Kaul, A. P. Cohen, R. E. Wood, and R. S. Amin Advances in the diagnosis and management of chronic pulmonary aspiration in children Eur. Respir. J., October 1, 2006; 28(4): 847 - 861. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J L Mathew, M Singh, and S K Mittal Gastro-oesophageal reflux and bronchial asthma: current status and future directions Postgrad. Med. J., December 1, 2004; 80(950): 701 - 705. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Khoshoo, T. Le, R. M. Haydel Jr, L. Landry, and C. Nelson Role of Gastroesophageal Reflux in Older Children With Persistent Asthma Chest, April 1, 2003; 123(4): 1008 - 1013. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Daoui, B. D'Agostino, L. Gallelli, X. Emonds Alt, F. Rossi, and C. Advenier Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation Eur. Respir. J., August 1, 2002; 20(2): 268 - 273. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B Avidan, A Sonnenberg, T G Schnell, and S J Sontag Temporal associations between coughing or wheezing and acid reflux in asthmatics Gut, December 1, 2001; 49(6): 767 - 772. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. K. Field, G. A. J. Gelfand, and S. D. McFadden The Effects of Antireflux Surgery on Asthmatics With Gastroesophageal Reflux Chest, September 1, 1999; 116(3): 766 - 774. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Contencin and P. Narcy Gastropharyngeal Reflux in Infants and Children: A Pharyngeal pH Monitoring Study Arch Otolaryngol Head Neck Surg, October 1, 1992; 118(10): 1028 - 1030. [Abstract] [PDF]
|
|
|
|
 |
|
 B. D. Sindel, M. J. Maisels, and T. V. N. Ballantine Gastroesophageal Reflux to the Proximal Esophagus in Infants With Bronchopulmonary Dysplasia Arch Pediatr Adolesc Med, September 1, 1989; 143(9): 1103 - 1106. [Abstract] [PDF]
|
|
|
|
|
|
P. McVeagh, R. Howman-Giles, and A. Kemp Pulmonary Aspiration Studied by Radionuclide Milk Scanning and Barium Swallow Roentgenography Arch Pediatr Adolesc Med, August 1, 1987; 141(8): 917 - 921. [Abstract] [PDF]
|
|
|
|
 |
|
 P. C. Harper, A. Bergner, and M. D. Kaye Antireflux Treatment for Asthma: Improvement in Patients With Associated Gastroesophageal Reflux Arch Intern Med, January 1, 1987; 147(1): 56 - 60. [Abstract] [PDF]
|
|
|
|
 |
|
 J. L. Allen and M. E. B. Wohl Pulmonary Function in Older Children and Young Adults with Gastroesophageal Reflux Clinical Pediatrics, November 1, 1986; 25(11): 541 - 546. [Abstract] [PDF]
|
|
|
|
|
|
S. Berezin, S. M. Schwarz, M. S. Halata, and L. J. Newman Gastroesophageal Reflux Secondary to Gastrostomy Tube Placement Arch Pediatr Adolesc Med, July 1, 1986; 140(7): 699 - 701. [Abstract] [PDF]
|
|
|
|
|
|
D. Thomas, R. M. Rothberg, and L. A. Lester Cystic Fibrosis and Gastroesophageal Reflux in Infancy Arch Pediatr Adolesc Med, January 1, 1985; 139(1): 66 - 67. [Abstract] [PDF]
|
|
