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PEDIATRICS Vol. 67 No. 3 March 1981, pp. 412-416
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Mortality of Chronic Hemodialysis and Renal Transplantation in Pediatric End-Stage Renal Disease

Ellis D. Avner MD1, William E. Harmon MD1, Warren E. Grupe MD1, Julie R. Ingelfinger MD1, Angelo J. Eraklis MD1, , Raphael H. Levey MD1

1 Division of Nephrology, Department of Medicine and the Department of Surgery, Children's Hospital Medical Center, Boston

The long-term mortality of chronic hemodialysis and renal transplantation was analyzed in all children treated for end-stage renal disease at Children's Hospital Medical Center over the past 8frac12 years. A total of 216 transplantation or dialysis courses in 120 patients were studied. No patients were excluded from treatment or analysis. Overall actuarial survival was 92% at six months, 90% at 12 months, and 89% at five years. When actuarial survival for each form of treatment was examined, patient survival was 100% at six months and 95% at five years for chronic hemodialysis; 92% at six months and five years for living related transplantation; and 88% at six months and 85% at five years for cadaveric transplantation. We conclude that most children with endstage renal disease can be kept alive with current treatment programs, and that the mortality of chronic hemodialysis in children is comparable to that of renal transplantation.

Submitted on April 24, 1980
Accepted on June 9, 1980


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Arch Pediatr Adolesc MedHome page
D. Ellis, E. D. Avner, J. T. Rosenthal, R. J. Taylor, L. W. Young, M. A. Palumbi, and T. R. Hakala
Renal Function and Somatic Growth in Pediatric Cadaveric Renal Transplantation With Cyclosporine-Prednisone Immunosuppression
Arch Pediatr Adolesc Med, November 1, 1985; 139(11): 1161 - 1167.
[Abstract] [PDF]