PEDIATRICS Vol. 66 No. 6 December 1980, pp. 865-869
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Aflatoxin and Reye's Syndrome: A Case Control Study

David B. Nelson MD1, Renate Kimbrough PhD1, Philip S. Landrigan MD1, A. Wallace Hayes PhD1, George C. Yang PhD1, Jeannette Benanides BS1, David M. Morens MD1, Dale Morse MD1, Marjorie Pollack MD1, Kenneth E. Powell MD1, and John Z. Sullivan-Bolyai MD1

1 Viral Disease Division and Chronic Disease Division, Bureau of Epidemiology, and Toxicology Division, Bureau of Laboratories, Center for Disease Control, Atlanta; Department of Pharmacology, University of Mississippi Medical Center, Jackson; and Food and Drug Administration, Washington, DC

Aflatoxin levels were determined in serum and urine of 17 patients with Reye's syndrome and in control subjects. No significant difference in aflatoxin levels was found for the two groups. However, 23% of all persons studied had levels of aflatoxin indicative of recent exposure. Aflatoxin levels were associated with ingestion of cornmeal and corn bread but not peanut-containing products. This prevalence of aflatoxin may be of public health importance.

Submitted on February 25, 1980
Accepted on April 23, 1980




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A.P. Wilkinson, D.W. Denning, and M.R.A. Morgan
Analysis of UK Sera for Aflatoxin by Enzyme-linked Immunosorbent Assay
Human and Experimental Toxicology, July 1, 1988; 7(4): 353 - 356.
[Abstract] [PDF]