PEDIATRICS Vol. 66 No. 4 October 1980, pp. 622-623
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Increased Intracranial Pressure Following Treatment of Cystic Fibrosis

Ewell Steve Roach MD1 and Sara Hendricks Sinal MD2

1 Department of Neurology
2 Department of Pediatrics, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina

Elevated intracranial pressure in children with cystic fibrosis has been previously attributed to vitamin A deficiency,1,2 which is a well recognized cause of increased intracranial pressure.3 Although there are several reports of suture diastasis after improvement of poor nutritional status,4-6 only one similar patient with a bulging fontanel following treatment of cystic fibrosis could be found in the literature.7

We have recently encountered two patients who developed bulging anterior fontanels soon after beginning treatment for cystic fibrosis. Both patients remained asymptomatic. A lumbar puncture demonstrated elevated intracranial pressure in one patient.

CASE REPORTS

Case 1

A 4frac12-month-old white male infant was admitted for evaluation of poor weight gain, vomiting, and intermittent diarrhea.




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J. V. Campellone, R. Nachajon, and C. M. Schramm
Acute Hydrocephalus Masquerading as Catch-Up Head Growth in an Infant with Cystic Fibrosis
Clinical Pediatrics, August 1, 1995; 34(8): 436 - 439.
[PDF]

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E.S. Roach and S. H. Sinal
Initial Treatment of Cystic Fibrosis: Frequency of Transient Bulging Fontanel
Clinical Pediatrics, August 1, 1989; 28(8): 371 - 373.
[Abstract] [PDF]