PEDIATRICS Vol. 66 No. 3 September 1980, pp. 403-404
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Chronic Granulomatous Disease and McLeod Syndrome in a Black Child

Senih M. Fikrig MD1, Juana C. D. Phillipp MD1, Elizabeth M. Smithwick MD1, Ragnhild Øyen 1, and William L. Marsh FIMLS, MI Biology1

1 State University of New York Downstate Medical Center, Brooklyn, the Memorial Sloan-Kettering Cancer Center, New York, and the Lindsley F. Kimball Research Institute, The New York Blood Center, New York

A 3-year-old black male child with X-linked chronic granulomatous disease and red cells of the rare McLeod phenotype is presented. The red cells showed acanthocytosis and did not react with anti-KL. Similarly the leukocytes were nonreactive with anti-Kx. The Xk and Xg linkage could not be investigated since all members of his family were Xg (a+).

Submitted on November 21, 1979
Accepted on December 26, 1979