PEDIATRICS Vol. 66 No. 2 August 1980, pp. 291-294
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Toxic Epidermal Necrolysis in Childhood: Differentiation from Staphylococcal Scalded Skin Syndrome

John P. Manzella MD1, Caroline B. Hall MD1, John L. Green MD1, and Thomas O. McMeekin MD1

1 Infectious Diseases Unit, Department of Medicine and Pediatrics, University of Rochester School of Medicine, Rochester, New York

The staphylococcal scalded skin syndrome usually occurs in children less than 5 years old, whereas drug-induced toxic epidermal necrolysis is considered a disease of adults.1 Except for the age differential, the two often cannot be distinguished clinically. Therefore, rapid and definitive biopsy diagnosis is essential in the management of patients with acute exfoliative skin disorders. We wish to report the case of a young child with proven toxic epidermal necrolysis and review the manifestations of this disease, as well as the staphylococcal scalded skin syndrome.

CASE REPORT

A 4-year-old white girl was admitted to Strong Memorial Hospital because of a generalized bullous eruption.




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