PEDIATRICS Vol. 65 No. 6 June 1980, pp. 1199
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Letters to the Editor

Harb Harfi MD1

1 1050 5th Avenue, Ft Worth, TX 76104

We would like to point out that the children we studied were known asthmatics whose symptoms had been controlled with oral theophyllin with, or without beta II agonists. All these patients had received either epinephrine parenterally or isoproterenal with IPPB before their admission, indicating the failure of these agents to control their asthma attacks.

The dosage of aminophyllin was relatively low (4 mg/kg) and none of the patients had toxic symptoms. Changing the aminophyllin dosage based on measurement of serum theophyllin could have added another variable which is not our purpose from the study, ie, the effect of high doses versus conventional doses of corticosteroids.