PEDIATRICS Vol. 65 No. 6 June 1980, pp. 1059-1067
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Echocardiographic Studies of the Human Fetus: Prenatal Diagnosis of Congenital Heart Disease and Cardiac Dysrhythmias

Charles S. Kleinman MD1, John C. Hobbins MD1, C. Carl Jaffe MD1, Diana C. Lynch RN1, and Norman S. Talner MD1

1 Departments of Pediatrics, Diagnostic Radiology, and Obstetrics and Gynecology, Yale University School of Medicine and Yale-New Haven Hospital, New Haven, Connecticut

During obstetrical ultrasound examinations, 200 M-mode and 35 real-time two-dimensional echocardiographic studies were performed on 180 fetuses of high-risk pregnancies. Fetal gestational ages ranged from 18 to 41 weeks. M-mode "sweeps" demonstrating mitral- and septal-aortic fibrous continuity were obtained in 115 studies. Paradoxic septal motion in 50 fetuses suggested relative right ventricular volume loading. Congenital cardiac malformations were accurately diagnosed in a 34-week fetus with pulmonary atresia and hypoplastic right ventricle and in a 28-week fetus with a univentricular heart. Congenital complete atrioventricular block was diagnosed in a 28-week fetus and atrial flutter with variable atrioventricular block was diagnosed in a 38-week fetus. The use of echocardiographic studies to evaluate cardiac structure and rhythm in utero assists in counseling prospective parents and in planning postnatal management for their offspring.

Submitted on June 13, 1979
Accepted on September 14, 1979




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